by Heather Millar
Alternet
February 23, 2013
Inside nanotechnology’s little universe of big unknowns.
This article first appeared at Orion Magazine under the title “Pandora’s Boxes.” You can enjoy future Orion articles by signing up to the magazine’s free trial subscription program.
A pair of scientists, sporting white clean-suits complete with helmets and face masks, approach a prefab agricultural greenhouse in a clearing at Duke University’s Research Forest. Inside are two long rows of wooden boxes the size of large horse troughs, which hold samples of the natural world that surrounds them—the pine groves and rhododendron thickets of North Carolina’s piedmont, which at this moment are alive with bird song.
Looking a lot like the government bad guys in E.T., the two men cautiously hover over a row of boxes containing native sedges, water grasses, and Zebra fish to spray a fine mist of silver nanoparticles over them. Their goal: to investigate how the world inside the boxes is altered by these essentially invisible and notoriously unpredictable particles.
The researchers are part of a multidisciplinary coalition of scientists from Duke, Stanford, Carnegie Mellon, Howard, Virginia Tech, and the University of Kentucky, headquartered at Duke’s Center for the Environmental Implications of NanoTechnology (CEINT), that represents one of the most comprehensive efforts yet to measure how nanoparticles affect ecosystems and biological systems.
So far the questions about whether nanoparticles are an environmental risk outnumber the answers, which is why the Duke scientists take the precaution of wearing clean-suits while dosing the boxes—no one’s sure what exposure to a high concentration of nanoparticles might do. Among the few things we do know about them are that they sail past the blood-brain barrier and can harm the nervous systems of some animals.
The regulation of nanoparticles has been recommended for more than a decade, but there’s no agreement on exactly how to do it. Meanwhile, the lid has already been lifted on nanotechnology. The use of man-made nanoparticles has spread into almost every area of our lives: food, clothing, medicine, shampoo, toothpaste, sunscreen, and thousands of other products.
Regulatory structures, both here and abroad, are completely unprepared for this onslaught of nanoproducts, because nanoparticles don’t fit into traditional regulatory categories. Additionally, companies often shield details about them by labeling them “proprietary”; they’re difficult to detect; we don’t have protocols for judging their effects; and we haven’t even developed the right tools for tracking them. If nanotechnology and its uses represent a frontier of sorts, it’s not simply the Wild West—it’s the Chaotic, Undiscovered, Uncontrollable West.
PN 
